Andarine (S4) or Acetamidoxolutamide, is a SARM (Selective Androgen Receptor Modulator). But the idea for S-4 didn’t start out as many believe.
It wasn’t an attempt to create a safer version of steroids or any of that nonsense people use to sell anabolics.
S-4 started out as a new development for male contraceptives and showed promising results like decreases in spermatogenesis and huge boosts in male libido. For any of you who have had trouble getting your wife pregnant while on sarms…you’re welcome.
However, when researchers began experimenting on mice with S4, they discovered interesting findings about how this first generation SARM affected castrated lab mice.
Not only did Andarine increase the production of muscle mass and calcium for bone density, but was COMPLETELY SELECTIVE in its tissue growth!
As studies continued, many of these research trials resulted in astonishing outcomes creating a benchmark for even more research.
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CARDADROL – Combining the most potent of SARMs into one superman product!
Cardarine GW 501516 (or Cardarine), is a research chemical developed in the 1990s to prevent and cure tumor formation in the colon, prostate, and breasts. Studies done in the early 2000s have found that GW 501516 and other PPAR agonists have also been able to stop metabolic disorders such as obesity and diabetes through specific gene expressions.
As research continued to grow, bodybuilders quickly caught on to GW 501516, calling it “the ultimate endurance enhancing supplement.”
Plus, Cardarine’s ability to burn off excess fatty tissue, enhance recovery, and dramatically increase endurance has made this product a staple in every athlete’s cycle and PCT. With no harmful side effects found in the past 20 years, no wonder why GW 501516 has become a legend in the world of sports and athleticism
Ligandrol LGD-4033 (VK5211) Ligandrol is an investigational selective androgen receptor modulator (SARM) for treatment of conditions such as muscle wasting and osteoporosis, discovered by Ligand Pharmaceuticals and currently under development by Viking Therapeutics
LGD-4033, known also as Ligandrol and Anabolicum, is the strongest orally bioavailable, non-steroidal, selective androgen receptor modulator (SARM) currently on the market.
Popular with athletes, power lifters and body builders for its ability to both bulk and cut, Ligandrol produces steroid-like results without the side effects.
It’s considered an excellent supplement for those looking to recomp: reduce their body fat and increase lean muscle mass.
From a medical perspective, Ligandrol is being studied to treat conditions such as muscle wasting linked with acute and chronic diseases, age-related muscle loss, Osteoporosis and cancer
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Cardarine or GW 501516, is a research chemical developed in the 1990s to prevent and cure tumor formation in the colon, prostate, and breasts. Studies done in the early 2000s have found that GW 501516 and other PPAR agonists have also been able to stop metabolic disorders such as obesity and diabetes through specific gene expressions.
As research continued to grow, bodybuilders quickly caught on to GW 501516, calling it “the ultimate endurance enhancing supplement.”
Plus, Cardarine’s ability to burn off excess fatty tissue, enhance recovery, and dramatically increase endurance has made this product a staple in every athlete’s cycle and PCT. With no harmful side effects found in the past 20 years, no wonder why GW 501516 has become a legend in the world of sports and athleticism.
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Ibutamoren (developmental code names MK 677, MK 0677, L-163,191; former tentative brand name Oratrope) is a potent, long-acting, orally-active, selective, and non-peptide agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It has been shown to increase the secretion of several hormones including GH and insulin-like growth factor 1 (IGF-1) and produces sustained increases in the plasma levels of these hormones without affecting cortisol levels.
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Ligandrol LGD-4033 (VK5211) Ligandrol is an investigational selective androgen receptor modulator (SARM) for treatment of conditions such as muscle wasting and osteoporosis, discovered by Ligand Pharmaceuticals and currently under development by Viking Therapeutics.
LGD-4033, known also as Ligandrol and Anabolicum, is the strongest orally bioavailable, non-steroidal, selective androgen receptor modulator (SARM) currently on the market.
Popular with athletes, powerlifters, and bodybuilders for its ability to both bulk and cut, Ligandrol produces steroid-like results without the side effects.
It’s considered an excellent supplement for those looking to recomp: reduce their body fat and increase lean muscle mass.
From a medical perspective, Ligandrol is being studied to treat conditions such as muscle wasting linked with acute and chronic diseases, age-related muscle loss, Osteoporosis, and cancer.
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Enobosarm, also known as ostarine, is an investigational selective androgen receptor modulator (SARM) developed by GTX, Inc for the treatment of conditions such as muscle wasting and osteoporosis, formerly under development by Merck & Company.
MK-2866, although totally safe, can provide subtle but consistent gains in muscle, size and strength in your rodent. It’s safe to say you can easily gain 5-10 lbs of muscle over several weeks.
What’s most important is that the gains you receive are lasting and will stay with you for the most part.
Some of the other benefits include:
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Testolone (RAD140) is a selective androgen receptor modulator (SARM) currently under development by Radius Health Inc. The intent of RAD140 is to serve as an alternative to testosterone replacement therapy. In the body, a normal dose of RAD140 mimics the effects of a LARGE DOSE of testosterone in muscle tissue but expresses a minimal affinity for non-muscular tissue. This results in substantially fewer undesirable side effects when compared with traditional anabolic steroids.
Clinical Uses
Provides anabolic support to test subjects with low testosterone levels (i.e. due to health issues, or prior abuse of anabolic steroids).
The bridge between anabolic steroid cycles. RAD140 is ideal to administer in between anabolic steroid cycles. After running PCT, RAD140 can be used to maintain muscle mass while the subject recovers and prepares for the next anabolic cycle.
Those who want to use a performance-enhancing drug, but are deterred by the negative side effects of running traditional anabolics.
Male subjects sensitive to gynecomastia. While RAD140 may produce effects similar to testosterone, it CANNOT aromatize to estrogen, therefore it can be used without fear of “gyno”, “man boobs”, or bloating.
Negative Side Effects:
As of this writing, RAD140 trials have shown an absence of side-effects normally associated with anabolics. Specifically, estrogen, progesterone, and prolactin-related side effects are ZERO.
Regarding HPG/HPTA suppression: All SARMs will exhibit a degree of suppression, and RAD140 is no exception. The key word here is suppression. Traditional anabolics don’t just suppress, they cause a complete shutdown. While some researchers dispute the ratio of LH/FSH/Testosterone suppression caused by SARMs, the bottom line is: SARMs suppress endogenous hormone production to a much lesser degree than traditional anabolics, making recovery MUCH faster. While we don’t necessarily recommend it as an optimal approach, many researchers opt to skip PCT for SARMs-only cycles.
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YK11, also known as Myostine, is considered one of the strongest SARMs on the market. In fact, it’s so strong and has a comparable anabolic activity to steroids that it may actually be a synthetic steroid that was mislabeled a SARM in the first place. YK11 was first studied by Japanese researcher Yuichiro Kanno in 2011. It was found to be a partial agonist of the Androgen Receptor (AR) with gene-selective properties, leading researchers to suggest that the compound is a SARM.
To date, limited studies have been undertaken, although preliminary findings in vitro on muscle cells are very promising. Initial studies suggest that YK11 may have greater muscle building effects than those of DHT and a propensity to act as a myostatin inhibitor. As a relatively new compound, exactly how YK11 works to improve lean muscle mass in humans can only be discussed based on initial in vitro studies. However, what we do know is that YK11 may be a Myostatin blocker – essentially allowing users to reap continuous gains without stalling and requiring a break in a cycle.
Myostatin is a protein that is released to limit muscle growth to ensure they do not get ‘too large’. It is found predominantly in skeletal muscle, and studies show that individuals with a gene mutation that limits Myostatin production are both stronger and more muscular than those with normal amounts. YK11 may help to inhibit the production of Myostatin in muscles by attaching itself to the Androgen Receptor. From there, it may induce muscles to create more Follistatin, which in turn limits the levels of Myostatin, allowing increased muscle growth beyond genetic capability.
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